HBVZ10, an AAV8 vector-based new HBV therapy candidate for cccDNA elimination

Eliminating hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) remains a major challenge, requiring innovative treatment strategies and drug candidates. Clinical studies reveal that wild-type HBV in the blood is often replaced by gradually rising mutant populations. This replacement ref...

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Bibliografski detalji

Glavni autori:	Bai-Hua Zhang, Yuanping Zhou, Stephen Horrigan, Laura Luckenbaugh, Jianming Hu, Fabien Zoulim, Yong-Yuan Zhang
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-12-01
Serija:	Molecular Therapy: Methods & Clinical Development
Teme:	HBVZ10 chronic HBV infection cccDNA elimination de novo infection AAV gene therapy
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2329050125002414
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