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Widespread gene-environment interactions shape the immune response to SARS-CoV-2 infection in hospitalized COVID-19 patients

Abstract Genome-wide association studies performed in COVID-19 patients have uncovered various loci significantly associated with susceptibility to SARS-CoV-2 infection and disease severity. However, the underlying cis-regulatory genetic factors contributing to heterogeneity in the response to SARS-...

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Autori principali: Haley E. Randolph, Raúl Aguirre-Gamboa, Elsa Brunet-Ratnasingham, Tomoko Nakanishi, Zepeng Mu, Veronica Locher, Ellen Ketter, Cary Brandolino, Catherine Larochelle, Alexandre Prat, Nathalie Arbour, Anne Dumaine, Andrés Finzi, Madeleine Durand, J. Brent Richards, Daniel E. Kaufmann, Luis B. Barreiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-04-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-026-72393-w
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