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PROTECTIVE EFFECT OF THE RAMELTEON, A MELATONIN AGONIST, AGAINST METHOTREXATE-INDUCED BONE-TOXICITY

Objective Methotrexate (MTX) used anti-metabolite, causes bone morbidity, including growth arrest and reduced bone mineral density. Melatonin, produced by the pineal gland, has also multiple positive effects in human bone cells, and positive effects on bone. Ramelteon (RMT) is a non-selective...

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Furkejuvvon:
Váldodahkkit: Recep Dinçer, Tuba Baykal, Duygu Kumbul Doğuç, Emine Sarman, Devran Ceylan
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Süleyman Demirel University 2022-03-01
Ráidu:Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi
Fáttát:
METHOTREXATE
RAMELTEON
MELATONIN
RUNX2
Catepsin K
Liŋkkat:https://dergipark.org.tr/tr/download/article-file/1911520
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