Reduced durability of hybrid immunity to SARS-CoV-2 in immunocompromised children

BackgroundIn endemic COVID-19, immunocompromised children are vulnerable until vaccinated but the optimal primary vaccination regime and need for booster doses remains uncertain.MethodsWe recruited 19 immunocompromised children (post-solid organ transplantation, have autoimmune disease or were on cu...

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Autori principali:	Youjia Zhong, Amuthavalli Kottaiswamy, Chen Xiang Ang, Hui’ En Li, Gaik Chin Yap, Carina J. X. Tay, Nurul Elyana Osman, Siti Namirah Binte Roslan, Chee Wah Tan, Wee Chee Yap, Elizabeth Y. Ang, Pauline P. L. Chan Ng, Hui Kim Yap, Liangjian Lu, Marion M. Aw, Sivaraman V. Karthik, Seng Hock Quak, Thuan Chong Quah, Elizabeth H. Tham, Lynette P. Shek, Eng Eong Ooi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-12-01
Serie:	Frontiers in Immunology
Soggetti:	adaptive immunity COVID-19 memory B cells T cells vaccine immunogenicity correlates of protection
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1502598/full
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