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Clinical complete response to serplulimab plus bevacizumab and chemotherapy in MSS/KRAS-mutant metastatic sigmoid colon adenocarcinoma: a case report and literature review

Mismatched-repair–proficient/microsatellite-stable (pMMR/MSS) metastatic colorectal cancer (mCRC) is typically refractory to immune checkpoint inhibitors. Early randomized data suggest that adding PD-1 blockade to anti-angiogenic therapy and oxaliplatin-based chemotherapy may improve outcomes, but r...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Qiao Luo, Haiyan Zhang, Binru Di, Yaowen Liu, Yulin Lei, Haixia Liu, Jianmei Wang, Luo Yuhao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2026-07-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1740803/full
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