Identification of SPP1 as an Extracellular Matrix Signature for Metastatic Castration-Resistant Prostate Cancer

Resistance to androgen deprivation therapy (ADT) is the main challenge for advanced fatal prostate cancer (PCa), which can gradually develop into metastatic castration-resistant prostate cancer (mCRPC). However, the pathologic mechanisms of mCRPC are still far from clear. Given the high incidence an...

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Principais autores:	Xiaocong Pang, Ran Xie, Zhuo Zhang, Qianxin Liu, Shiliang Wu, Yimin Cui
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-09-01
Colecção:	Frontiers in Oncology
Assuntos:	SPP1 castration-resistant prostate cancer extracellular matrix metastasis organoid model
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fonc.2019.00924/full
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