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OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1

Abstract Background Deubiquitinating enzymes (DUBs) cleave ubiquitin on substrate molecules to maintain protein stability. DUBs reportedly participate in the tumorigenesis and tumour progression of hepatocellular carcinoma (HCC). OTU deubiquitinase 5 (OTUD5), a DUB family member, has been recognized...

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Principais autores: Yingnan Yang, Siying Jia, Ning Zhu, Xuelian Xiao, Ying Ma, Kangsheng Tu, Yong Guo, Qiuran Xu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-04-01
Serier:Biology Direct
Fag:
Hepatocellular carcinoma
Deubiquitinating enzymes
OTUD5, SLC38A1, Tumour growth
Online adgang:https://doi.org/10.1186/s13062-024-00475-0
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