Synthesis and Sar Study of Diarylpentanoid Analogues as New Anti-Inflammatory Agents

A series of ninety-seven diarylpentanoid derivatives were synthesized and evaluated for their anti-inflammatory activity through NO suppression assay using interferone gamma (IFN-γ)/lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Twelve compounds (9, 25, 28, 43, 63, 64, 81, 83, 84, 86, 88...

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Bibliografiska uppgifter

Huvudupphov:	Sze Wei Leong, Siti Munirah Mohd Faudzi, Faridah Abas, Mohd Fadhlizil Fasihi Mohd Aluwi, Kamal Rullah, Lam Kok Wai, Mohd Nazri Abdul Bahari, Syahida Ahmad, Chau Ling Tham, Khozirah Shaari, Nordin H. Lajis
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2014-10-01
Serie:	Molecules
Ämnen:	anti-inflammatory diarylpentanoid RAW 264.7 curcumin SAR pharmacophore
Länkar:	http://www.mdpi.com/1420-3049/19/10/16058
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