Biophysical Interactions Underpin the Emergence of Information in the Genetic Code

The genetic code conceals a ‘code within the codons’, which hints at biophysical interactions between amino acids and their cognate nucleotides. Yet, research over decades has failed to corroborate systematic biophysical interactions across the code. Using molecular dynamics simulations and NMR, we...

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Autors principals:	Aaron Halpern, Lilly R. Bartsch, Kaan Ibrahim, Stuart A. Harrison, Minkoo Ahn, John Christodoulou, Nick Lane
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-05-01
Col·lecció:	Life
Matèries:	origin of life genetic code biophysical interactions hydrophobicity anticodon molecular dynamics
Accés en línia:	https://www.mdpi.com/2075-1729/13/5/1129
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