Profile hidden Markov model sequence analysis can help remove putative pseudogenes from DNA barcoding and metabarcoding datasets

Abstract Background Pseudogenes are non-functional copies of protein coding genes that typically follow a different molecular evolutionary path as compared to functional genes. The inclusion of pseudogene sequences in DNA barcoding and metabarcoding analysis can lead to misleading results. None of t...

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Bibliografische Detailangaben

Hauptverfasser:	T. M. Porter, M. Hajibabaei
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2021-05-01
Schriftenreihe:	BMC Bioinformatics
Schlagworte:	Nuclear encoded mitochondrial sequences Pseudogene NuMT Bioinformatics COI mtDNA DNA barcode
Online-Zugang:	https://doi.org/10.1186/s12859-021-04180-x
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