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Convergent Synthesis of Two Fluorescent Ebselen-Coumarin Heterodimers

The organo-seleniumdrug ebselen exhibits a wide range of pharmacological effects that are predominantly due to its interference with redox systems catalyzed by seleno enzymes, e.g., glutathione peroxidase and thioredoxin reductase. Moreover, ebselen can covalently interact with thiol groups of sever...

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Autors principals: Jim Küppers, Anna Christina Schulz-Fincke, Jerzy Palus, Mirosław Giurg, Jacek Skarżewski, Michael Gütschow
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2016-07-01
Col·lecció:Pharmaceuticals
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Accés en línia:http://www.mdpi.com/1424-8247/9/3/43
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