Long-term DNA methylation changes induced by age and elevated CO2 in skeletal muscle

Abstract Background Skeletal muscle dysfunction and elevated CO2 in the blood, or hypercapnia, are both associated with higher mortality in acute and chronic pulmonary diseases. Hypercapnia-, aging and autophagy dysfunction-induced skeletal muscle phenotypes are highly overlapping. While DNA methyla...

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Autors principals:	Joseph Balnis, Andy Madrid, Emily L. Jackson, Lisa A. Drake, Catherine E. Vincent, Harold A. Singer, Reid S. Alisch, Ariel Jaitovich
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-12-01
Col·lecció:	Skeletal Muscle
Matèries:	Hypercapnia Skeletal muscle DNA methylation Autophagy Aging
Accés en línia:	https://doi.org/10.1186/s13395-025-00406-1
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