Domain innovation and deeply conserved intrinsic disorders in eukaryotic argonauteDomain innovation and deeply conserved intrinsic disorders in eukaryotic argonaute

AbstractArgonaute (Ago) proteins are distributed across all domains of life and play central roles in the defence against mobile genetic elements. We performed extensive searches of Ago proteins across eukaryotes. We revealed wide variability in the genomic content of Agos and unprecedented diversit...

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Autori principali:	Diego Forni, Rachele Cagliani, Alessandra Mozzi, Roudin Sarama, Uberto Pozzoli, Manuela Sironi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	The Royal Society 2026-07-01
Serie:	Open Biology
Soggetti:	Argonaute proteins PIWI domain intrinsically disordered regions conformational properties
Accesso online:	https://royalsocietypublishing.org/rsob/article-pdf/doi/10.1098/rsob.260067/6150855/rsob260067.pdf
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