The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.
IKAROS is a critical regulator of hematopoietic cell fate and its dynamic expression pattern is required for proper hematopoiesis. In collaboration with the Nucleosome Remodeling and Deacetylase (NuRD) complex, it promotes gene repression and activation. It remains to be clarified how IKAROS can sup...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2014-12-01
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| Series: | PLoS Genetics |
| Acceso en liña: | http://europepmc.org/articles/PMC4256266?pdf=render |
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