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In silico and cheminformatics prediction with experimental validation of an adipogenesis cocktail, sorafenib with rosiglitazone for HCC dedifferentiation

Purpose: Hepatocellular carcinoma (HCC) resistance to sorafenib treatment and other treatment strategies causes a higher mortality rate in patients diagnosed with HCC.Research question.HCC often develops resistance to sorafenib treatment and other therapies, leading to increased mortality rates in d...

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Principais autores: Aya Anis, Ahmed M. Mostafa, Mariam S. Kerema, Nadia M. Hamdy, Ahmed S. Sultan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-12-01
coleção:Journal of Genetic Engineering and Biotechnology
Assuntos:
Rosiglitazone
Insulin
IBMX, PPARγ
HCC
Sorafenib
Adipogenesis-inducer
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1687157X2400132X
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