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Adenosine A<sub>2A</sub> receptor activation reduces recurrence and mortality from <it>Clostridium difficile</it> infection in mice following vancomycin treatment

<p>Abstract</p> <p>Background</p> <p>Activation of the A<sub>2A</sub> adenosine receptor (A<sub>2A</sub>AR) decreases production of inflammatory cytokines, prevents <it>C</it>. <it>difficile</it> toxin A-induced enteritis and, in combination with antibiotics, increases survival from sepsis in mice....

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Autori principali: Li Yuesheng, Figler Robert A, Kolling Glynis, Bracken Tara C, Rieger Jayson, Stevenson Ralph W, Linden Joel, Guerrant Richard L, Warren Cirle
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-12-01
Serie:BMC Infectious Diseases
Soggetti:
<it>C</it>. <it>difficile</it>
Colitis
Adenosine A<sub>2A</sub> receptor
Diarrhea
Accesso online:http://www.biomedcentral.com/1471-2334/12/342
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