Dual Inhibition of PB2 and JAK2 for Influenza: A Strategy Combining Antiviral and Host-Directed Immune Modulation

Influenza virus infection remains a major global health burden, with severe disease outcomes driven not only by viral replication but also by excessive host inflammatory responses. Current antiviral therapies predominantly target viral components and fail to adequately control virus-induced hyperinf...

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Principais autores:	Binhao Rong, Yujian Yang, Kunyu Lu, Xingyu Zhou, Peisen Zheng, Xinxin Lin, Yuanmei Wen, Shudong Lin, Xinshan Deng, Qifan Zhou, Shuwen Liu
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2026-02-01
Serija:	Molecules
Teme:	influenza virus dual-target inhibitor PB2 cap-binding domain JAK-STAT signaling antiviral anti-inflammatory
Online dostop:	https://www.mdpi.com/1420-3049/31/4/696
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