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Condensate cooperativity underlies transgenerational gene silencing

Summary: Biomolecular condensates have been shown to interact in vivo, yet it is unclear whether these interactions are functionally meaningful. Here, we demonstrate that cooperativity between two distinct condensates—germ granules and P bodies—is required for transgenerational gene silencing in C. ...

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Principais autores: Zhenzhen Du, Kun Shi, Jordan S. Brown, Tao He, Wei-Sheng Wu, Ying Zhang, Heng-Chi Lee, Donglei Zhang
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2023-08-01
Serija:Cell Reports
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2211124723008707
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