Genomic profiling and HER2-targeted therapy: a case series of Chinese salivary duct carcinoma patients and its clinical implications

PurposeSalivary duct carcinoma (SDC) is a rare and aggressive subtype of salivary gland cancers (SGCs). Currently, there is no approved targeted therapy for this devastating disease. This study aimed to identify actionable genomic alterations in Chinese patients with SDC and explore the clinical eff...

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Hauptverfasser:	Xiang Huang, Wei Yu, Xiaomo Li, Boning Cai, Baolin Qu, Jing Chen, Pei Zhang, Xinrui Chen, Yanli Liu, Shengqiang Feng, Lin Gui, Fang Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2026-02-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	driver mutation HER2-targeted therapy pertuzumab pyrotinib salivary duct carcinoma trastuzumab
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2026.1727362/full
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