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Mechanisms of resistance to EGFR tyrosine kinase inhibitors

Since the discovery that non-small cell lung cancer (NSCLC) is driven by epidermal growth factor receptor (EGFR) mutations, the EGFR tyrosine kinase inhibitors (EGFR-TKIs, e.g., gefitinib and elrotinib) have been effectively used for clinical treatment. However, patients eventually develop drug resi...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Lihua Huang, Liwu Fu
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2015-09-01
Rangatū:Acta Pharmaceutica Sinica B
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2211383515001045
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