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Impact of B-Ring Substitution on the Anti-Inflammatory Activity of Nitrochalcones

A series of three chalcones with a nitro moiety in ring B (compounds <b>3a–c</b>) was obtained by following a classic Claisen–Schmidt condensation procedure, which involved hydro-alcoholic conditions at room temperature. The reaction yields are consistently high (>90%), and the spectroscopic data ar...

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Autores principales: Erika Alarcón-Matus, Alam Yair Hidalgo, Carlos Ernesto Lobato-García, Abraham Gómez-Rivera, Luis Fernando Roa de la Fuente, Cuauhtémoc Alvarado-Sánchez, Hidemí Aguilar-Mariscal, Miguel Ángel Vilchis-Reyes, Nancy Romero Ceronio
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2025-11-01
Colección:Chemistry Proceedings
Materias:
nitro-chalcone
Claisen condensation
ring A
ring B
comparison
anti-inflammatory protective effect
Acceso en línea:https://www.mdpi.com/2673-4583/18/1/96
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