An open microfluidic coculture model of fibroblasts and eosinophils to investigate mechanisms of airway inflammation

Interactions between fibroblasts and immune cells play an important role in tissue inflammation. Previous studies have found that eosinophils activated with interleukin-3 (IL-3) degranulate on aggregated immunoglobulin G (IgG) and release mediators that activate fibroblasts in the lung. However, the...

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Detalhes bibliográficos

Principais autores:	Yuting Zeng, Xiaojing Su, Meg G. Takezawa, Paul S. Fichtinger, Ulri N. Lee, Jeffery W. Pippin, Stuart J. Shankland, Fang Yun Lim, Loren C. Denlinger, Nizar N. Jarjour, Sameer K. Mathur, Nathan Sandbo, Erwin Berthier, Stephane Esnault, Ksenija Bernau, Ashleigh B. Theberge
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-09-01
coleção:	Frontiers in Bioengineering and Biotechnology
Assuntos:	open microfluidics coculture inflammation eosinophils fibroblasts cell signaling
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbioe.2022.993872/full
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