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Alzheimer’s Disease Polygenic Risk Score Is Not Associated With Cognitive Decline Among Older Adults With Type 2 Diabetes

ObjectivesMultiple risk loci for late-onset Alzheimer’s disease (LOAD) have been identified. Type 2 diabetes (T2D) is a risk factor for cognitive decline, dementia and Alzheimer’s disease (AD). We investigated the association of polygenic risk score (PRS) for LOAD with overall cognitive functioning...

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Bibliografski detalji
Glavni autori: Sigalit B. Manzali, Eric Yu, Ramit Ravona-Springer, Abigail Livny, Sapir Golan, Yuxia Ouyang, Orit Lesman-Segev, Lang Liu, Ithamar Ganmore, Anna Alkelai, Ziv Gan-Or, Hung-Mo Lin, Anthony Heymann, Michal Schnaider Beeri, Lior Greenbaum
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2022-08-01
Serija:Frontiers in Aging Neuroscience
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fnagi.2022.853695/full
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