Serum levels of soluble TNF-α receptors but not BDNF are associated with apathy symptoms in mild Alzheimer's disease and amnestic mild cognitive impairment

ABSTRACT Apathy is intimately associated with dementia. Unfortunately, its pathophysiology remains poorly understood. The motivational impairment that characterizes this disorder might share the same inflammatory mechanisms, as suggested by the sickness behavior theory. Objective: The primary aim o...

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Hlavní autoři:	Henrique Cerqueira Guimarães, Paulo Caramelli, Patricia Paes Araujo Fialho, Elisa de Paula França, Marcelo Pelizzaro Dias Afonso, Antonio Lucio Teixeira
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
Edice:	Dementia & Neuropsychologia
Témata:	apathy dementia Alzheimer's disease mild cognitive impairment TNF-α sTNFR1 sTNFR2 BDNF.
On-line přístup:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642013000300298&lng=en&tlng=en
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