Structure-Aware Mycobacterium tuberculosis Functional Annotation Uncloaks Resistance, Metabolic, and Virulence Genes

ABSTRACT Accurate and timely functional genome annotation is essential for translating basic pathogen research into clinically impactful advances. Here, through literature curation and structure-function inference, we systematically update the functional genome annotation of Mycobacterium tuberculos...

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Bibliografische Detailangaben

Hauptverfasser:	Samuel J. Modlin, Afif Elghraoui, Deepika Gunasekaran, Alyssa M. Zlotnicki, Nicholas A. Dillon, Nermeeta Dhillon, Norman Kuo, Cassidy Robinhold, Carmela K. Chan, Anthony D. Baughn, Faramarz Valafar
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2021-12-01
Schriftenreihe:	mSystems
Schlagworte:	Mycobacterium tuberculosis annotation structure virulence factors functional genomics pyrazinamide
Online-Zugang:	https://journals.asm.org/doi/10.1128/mSystems.00673-21
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