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Effect of thrombopoietin-receptor agonists on circulating cytokine and chemokine levels in patients with primary immune thrombocytopenia (ITP)

Background: Thrombopoietin-receptor-agonists (TPO-RAs) increase platelet production in Immune Thrombocytopenia (ITP) by stimulating Mpl. The effect of TPO-RAs on inflammatory cytokine production in ITP patients has not been well investigated. Methods: Plasma samples from 48 ITP patients treated with...

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Principais autores: Sif Gudbrandsdottir, Waleed Ghanima, Claus H Nielsen, Xingmin Feng, Hans C Hasselbalch, James Bussel
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2017-07-01
Serier:Platelets
Fag:
chemokines
cytokines
primary immune thrombocytopenia
thrombopoietin-receptor agonists
Online adgang:http://dx.doi.org/10.1080/09537104.2016.1235691
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