Safety evaluation of irinotecan: a real-world disproportionality analysis using FAERS and JADER databases during the time period 2004-2024

IntroductionIrinotecan is a widely used chemotherapeutic agent for treating colorectal, pancreatic, and ovarian cancers. Despite its therapeutic efficacy, the safety profile of irinotecan necessitates continuous pharmacovigilance due to its association with severe adverse drug events (ADEs). Given i...

Descrición completa

Detalles Bibliográficos

Principais autores:	Siyu Lou, Huayou Chen, Zhiwei Cui, Xiyuan Zhang, Chengyu Zhu, Linmei Zhou, Yingyong Ou, Fan Zou
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Pharmacology
Assuntos:	irinotecan real-world pharmacovigilance analysis FAERS JADER adverse drug event
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1516449/full
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!