An Activatable T₁-Weighted MR Contrast Agent: A Noninvasive Tool for Tracking the Vicinal Thiol Motif of Thioredoxin in Live Cells

We have synthesized new magnetic resonance imaging (MRI) T₁ contrast agents (CA1 and CA2) that permit the activatable recognition of the cellular vicinal thiol motifs of the protein thioredoxin. The contrast agents showed MR relaxivities typical of gadolinium complexes with a single water...

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Bibliografische gegevens

Hoofdauteurs:	Jongeun Kang, Eunha Hwang, Hyunseung Lee, Mi Young Cho, Sanu Karan, Hak Nam Kim, Jong Seung Kim, Jonathan L. Sessler, Sankarprasad Bhuniya, Kwan Soo Hong
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2021-04-01
Reeks:	Molecules
Onderwerpen:	MR relaxivity activatable contrast thioredoxin vicinal thiols
Online toegang:	https://www.mdpi.com/1420-3049/26/7/2018
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