Novel strategies for vancomycin-resistant Enterococcus faecalis biofilm control: bacteriophage (vB_EfaS_ZC1), propolis, and their combined effects in an ex vivo endodontic model

Abstract Background Endodontic treatment failures are predominantly attributed to Enterococcus faecalis (E. faecalis) infection, a Gram-positive coccus. E. faecalis forms biofilms, resist multiple antibiotics, and can withstand endodontic disinfection protocols. Vancomycin-resistant strains, in part...

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Autors principals:	Toka A. Hakim, Bishoy Maher Zaki, Dalia A. Mohamed, Bob Blasdel, Mohamed A. Gad, Mohamed S. Fayez, Ayman El-Shibiny
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-04-01
Col·lecció:	Annals of Clinical Microbiology and Antimicrobials
Matèries:	Antibiofilm Endodontic treatment Irrigation Phage therapy Propolis Saphexavirus
Accés en línia:	https://doi.org/10.1186/s12941-025-00790-y
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