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Glutathione Metabolism Contributes to the Induction of Trained Immunity

The innate immune system displays heterologous memory characteristics, which are characterized by stronger responses to a secondary challenge. This phenomenon termed trained immunity relies on epigenetic and metabolic rewiring of innate immune cells. As reactive oxygen species (ROS) production has b...

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Furkejuvvon:
Váldodahkkit: Anaisa V. Ferreira, Valerie A. C. M. Koeken, Vasiliki Matzaraki, Sarantos Kostidis, Juan Carlos Alarcon-Barrera, L. Charlotte J. de Bree, Simone J. C. F. M. Moorlag, Vera P. Mourits, Boris Novakovic, Martin A. Giera, Mihai G. Netea, Jorge Domínguez-Andrés
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2021-04-01
Ráidu:Cells
Fáttát:
glutathione
trained immunity
macrophages
metabolism
innate immune memory
Liŋkkat:https://www.mdpi.com/2073-4409/10/5/971
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