Exposure of Keratinocytes to Candida Albicans in the Context of Atopic Milieu Induces Changes in the Surface Glycosylation Pattern of Small Extracellular Vesicles to Enhance Their Propensity to Interact With Inhibitory Siglec Receptors

Candida albicans (C. albicans) infection is a potential complication in the individuals with atopic dermatitis (AD) and can affect clinical course of the disease. Here, using primary keratinocytes we determined that atopic milieu promotes changes in the interaction of small extracellular vesicles (s...

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Principais autores:	Adrian Kobiela, Joanna E. Frackowiak, Anna Biernacka, Lilit Hovhannisyan, Aleksandra E. Bogucka, Kinga Panek, Argho Aninda Paul, Joanna Lukomska, Xinwen Wang, Eleni Giannoulatou, Aleksandra Krolicka, Jacek Zielinski, Milena Deptula, Michal Pikula, Susanne Gabrielsson, Graham S. Ogg, Danuta Gutowska-Owsiak
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Immunology
Assuntos:	Candida albicans glycosylation extracellular vesicle keratinocyte siglec atopic dermatitis (AD)
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.884530/full
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