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Listeriolysin O Causes ENaC Dysfunction in Human Airway Epithelial Cells

Pulmonary permeability edema is characterized by reduced alveolar Na+ uptake capacity and capillary barrier dysfunction and is a potentially lethal complication of listeriosis. Apical Na+ uptake is mainly mediated by the epithelial sodium channel (ENaC) and initiates alveolar liquid clearance. Here...

Täydet tiedot

Tallennettuna:
Päätekijät: Guang Yang, Helena Pillich, Richard White, Istvan Czikora, Isabelle Pochic, Qiang Yue, Martina Hudel, Boris Gorshkov, Alexander Verin, Supriya Sridhar, Carlos M. Isales, Douglas C. Eaton, Jürg Hamacher, Trinad Chakraborty, Rudolf Lucas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2018-02-01
Sarja:Toxins
Aiheet:
listeriolysin O
TNF
pulmonary permeability edema
epithelial sodium channel
protein kinase C-α
Linkit:http://www.mdpi.com/2072-6651/10/2/79
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