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Phlorotannins from <i>Ecklonia cava</i> Regulate Dual Signaling Pathways, IL-17RA/Act1 and ERK1/2, to Suppress Ovarian Cancer Progression and Tumor-Associated Macrophage Activation

Background: Marine-derived secondary metabolites such as phlorotannins from the edible brown alga <i>Ecklonia cava</i> exhibit diverse bioactivities. However, their mechanisms in inflammation-associated cancer remain insufficiently understood. Methods: This study explored the anticancer potential of...

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Principais autores: Eun-Hye Kim, Hwi-Ho Lee, Jung-Hye Choi, Ji-Hye Ahn
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-12-01
Serier:Marine Drugs
Fag:
<i>Ecklonia cava</i>
phlorotannins
IL-17RA/Act1 pathway
ERK1/2
ovarian cancer invasion
tumor-associated macrophages
Online adgang:https://www.mdpi.com/1660-3397/24/1/12
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