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Case report: Concomitant EGFR mutation and ALK rearrangement in non-small cell lung cancer

In non-small cell lung cancer (NSCLC), two key genetic alterations, epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements, are commonly believed to be mutually exclusive. Studies have reported that concurrent EGFR/ALK co-mutation in non-small cell lung...

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Main Authors: Haoyue Hu, Songtao Tan, Meng Xie, Peng Guo, Qiang Yu, Juan Xiao, Kangrui Zhao, Qiong Liao, Yi Wang
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Pharmacology
Subjects:
ALK rearrangement
EGFR mutation
lung adenocarcinoma
targeted therapy
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1167959/full
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