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Ribosomal RNA synthesis by RNA polymerase I is subject to premature termination of transcription

The RNA polymerase I (Pol I) enzyme that synthesizes large rRNA precursors exhibits a high rate of pauses during elongation, indicative of a discontinuous process. We show here that premature termination of transcription (PTT) by Pol I in yeast Saccharomyces cerevisiae is a critical regulatory step...

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Detalles Bibliográficos
Principais autores: Chaïma Azouzi, Katrin Schwank, Sophie Queille, Marta Kwapisz, Marion Aguirrebengoa, Anthony Henras, Simon Lebaron, Herbert Tschochner, Annick Lesne, Frederic Beckouët, Olivier Gadal, Christophe Dez
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications Ltd 2026-02-01
Series:eLife
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Acceso en liña:https://elifesciences.org/articles/106503
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