Higher Cytokine and Opsonizing Antibody Production Induced by Bovine Serum Albumin (BSA)-Conjugated Tetrasaccharide Related to Streptococcus pneumoniae Type 3 Capsular Polysaccharide

A number of studies have demonstrated the limited efficacy of S. pneumoniae type 3 capsular polysaccharide (CP) in the 13-valent pneumococcal conjugate vaccine against serotype 3 invasive pneumococcal diseases and carriage. Synthetic oligosaccharides (OSs) may provide an alternative to CPs for devel...

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Autors principals:	Ekaterina A. Kurbatova, Nelli K. Akhmatova, Anton E. Zaytsev, Elina A. Akhmatova, Nadezhda B. Egorova, Natalya E. Yastrebova, Elena V. Sukhova, Dmitriy V. Yashunsky, Yury E. Tsvetkov, Nikolay E. Nifantiev
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2020-12-01
Col·lecció:	Frontiers in Immunology
Matèries:	Streptococcus pneumoniae type 3 synthetic oligosaccharide biotinylated oligosaccharide conjugated oligosaccharide antigen-binding capacity vaccine
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2020.578019/full
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