Antagonistic antiviral activity between IFN-lambda and IFN-alpha against lethal Crimean-Congo hemorrhagic fever virus in vitro.

<h4>Background and aims</h4>Crimean Congo Hemorrhagic fever virus (CCHFV) is the causative agent of Crimean-Congo hemorrhagic fever, a severe disease with a mortality rate of around 30% in humans. Previous studies demonstrate that pre-treatment with type I IFNs have an antiviral effect against CCHFV...

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Autori principali:	Licia Bordi, Eleonora Lalle, Claudia Caglioti, Damiano Travaglini, Daniele Lapa, Patrizia Marsella, Serena Quartu, Zoltan Kis, Kevin K Arien, Hartwig P Huemer, Silvia Meschi, Giuseppe Ippolito, Antonino Di Caro, Maria R Capobianchi, Concetta Castilletti
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2015-01-01
Serie:	PLoS ONE
Accesso online:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0116816&type=printable
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