Regulation of T cell tissue residency and activation in human PCLS

Abstract Background Resident immune cells are central in shaping the lung’s tissue-specific immunity. Precision-cut lung slices (PCLS) preserve the native tissue microenvironment and are therefore an excellent ex vivo model to analyze residency and functionality of resident memory T cells. Methods T...

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Autors principals:	Tonia Bargmann, Charline Sommer, Lena Stowasser, Sophie Jacob, Louisa Jürgen, Sebastian Konzok, Christopher Werlein, Patrick Zardo, Lavinia Neubert, Danny Jonigk, Hans-Gerd Fieguth, Franziska Dahlmann, Katherina Sewald, Susann Dehmel, Armin Braun
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-11-01
Col·lecció:	Respiratory Research
Matèries:	PCLS Ex vivo Resident memory t cells Recall response MHC-I peptides Polyclonal t cell activation
Accés en línia:	https://doi.org/10.1186/s12931-025-03397-1
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