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LncRNA CISTR-ACT regulates cell size in human and mouse by guiding FOSL2

Abstract Organisms regulate cell size and shape to function efficiently. Aberrant cell morphogenesis is commonly associated with disease, yet gene-regulatory mechanisms remain unknown. CISTR-ACT was the first lncRNA involved in inter-chromosomal proximities and Mendelian disease, and it is associate...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Katerina Kiriakopulos, Katty Soleimanpour, Brandon J. McMurray, Benjamin-Israel Moke, Jordan J. Chalmers, Milad Mokhtaridoost, Jeremy D. Newton, Taylor De Young, Kate Delfosse, Mai Ahmed, Cassandra J. Wong, Sigmar Stricker, Yun Li, Brian J. Nieman, Anne-Claude Gingras, Monica J. Justice, Julie L. Lefebvre, Philipp G. Maass
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-12-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-025-67591-x
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