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Efficacy, safety, and immunogenicity of SARS-CoV-2 mRNA vaccine (Omicron BA.5) LVRNA012: a randomized, double-blind, placebo-controlled phase 3 trial

BackgroundWe aimed to evaluate the efficacy, safety, and immunogenicity of a SARS-CoV-2 mRNA vaccine (Omicron BA.5) LVRNA012 given as the booster in immunized but SARS-CoV-2 infection-free adults in China.MethodsThis is a single-center, randomized, double-blind, placebo-controlled phase 3 clinical t...

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Principais autores: Huan Zhou, Hui Zheng, Yucai Peng, Yue Su, Xuya Yu, Weixiao Wang, Simin Li, Yuzhou Ding, Shiping Jiao, Ying Wang, Xingyu Zhu, Liping Luo, Ziyong Dong, Lu Liu, Fan Zhang, Qiang Wu, Jingxin Li, Fengcai Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-06-01
coleção:Frontiers in Immunology
Assuntos:
COVID-19
mRNA vaccine
booster dose
heterologous immunization
inactivated vaccine
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1407826/full
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