Efficacy and mechanism of combined treatment with transcranial direct current stimulation and zolpidem for treatment-resistant insomnia: a study protocol for a prospective, double-blind, randomized controlled trial

BackgroundTreatment-resistant insomnia remains a major unmet clinical challenge, as a substantial proportion of patients fail to achieve long-term remission with cognitive behavioral therapy or pharmacotherapy alone. Transcranial direct current stimulation (tDCS) has shown promise in modulating cort...

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Hlavní autoři:	Yudong Wang, Jian Liu, Shanshan Cheng, Jun-Li Cao, Jianyou Zhang, Luo Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-02-01
Edice:	Frontiers in Psychiatry
Témata:	combined therapy functional magnetic resonance imaging transcranial direct current stimulation treatment-resistant insomnia zolpidem
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1743024/full
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