Synthesis of conformationally restricted glutamate and glutamine derivatives from carbonylation of orthopalladated phenylglycine derivatives

A new method for the regioselective synthesis of 2-alkoxycarbonyl- and 2-(aminocarbonyl)phenylglycinate methyl esters has been developed. The reaction of the orthopalladated complex [Pd(μ-Cl)(C6H4(CH(CO2Me)NMe2)-2)]2 (1) with nucleophiles HNu under a CO atmosphere results in the selective incorporat...

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Detalhes bibliográficos

Principais autores:	Esteban P. Urriolabeitia, Eduardo Laga, Carlos Cativiela
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Beilstein-Institut 2012-09-01
coleção:	Beilstein Journal of Organic Chemistry
Assuntos:	C–H functionalization carbonylation glutamic acid glutamide palladium phenylglycine
Acesso em linha:	https://doi.org/10.3762/bjoc.8.179
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