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Chronic O-GlcNAcylation and Diabetic Cardiomyopathy: The Bitterness of Glucose

Type 2 diabetes (T2D) is a major risk factor for heart failure. Diabetic cardiomyopathy (DC) is characterized by diastolic dysfunction and left ventricular hypertrophy. Epidemiological data suggest that hyperglycaemia contributes to the development of DC. Several cellular pathways have been implicat...

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Principais autores: Simon Ducheix, Jocelyne Magré, Bertrand Cariou, Xavier Prieur
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018-10-01
Serija:Frontiers in Endocrinology
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Online dostop:https://www.frontiersin.org/article/10.3389/fendo.2018.00642/full
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