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RNA binding protein ALYREF regulates ferroptosis to facilitate LUAD growth and metastasis via promoting SLC7A11 mRNA stability

Abstract Ferroptosis is of great significance in carcinogenesis as it interconnects with a multiplicity of biological processes. Meanwhile, its function and regulatory role in lung cancer remains ambiguous. In this study, we discovered by WB and IHC that ALYREF has a higher expression in lung adenoc...

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Detalhes bibliográficos
Principais autores: Yanni Chen, Ting Zhao, Hao Chen, Jun Chen, Weili Han
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-01-01
coleção:Scientific Reports
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Acesso em linha:https://doi.org/10.1038/s41598-024-83276-9
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