Optimizing HLA desensitization: serum dilution strategies and platform-specific MFI thresholds for antibody-mediated rejection risk in kidney transplantation

IntroductionHighly sensitized kidney transplant (KT) candidates are at increased risk of antibody-mediated rejection (ABMR), particularly in the context of desensitization protocols. Accurate quantification of donor-specific antibodies (DSA) using Luminex single antigen bead (SAB) assays remains ess...

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Principais autores:	Dominique Bertrand, Céline Dard, Rangolie Kaveri, Thomas Jouve, Paolo Malvezzi, Lionel Rostaing, Dominique Guerrot, Mathilde Lemoine, Charlotte Laurent, Johan Noble, Fabienne Farce
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2025-10-01
Series:	Frontiers in Immunology
Assuntos:	desensitization HLA kidney transplantation luminex highly sensitized dilution
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1661977/full
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