Pleiotropic and multicellular roles of lymphotoxin beta receptor in solid tumor immunity and therapeutic targeting

Immunotherapy has transformed the treatment landscape of several malignancies, yet solid tumors such as pancreatic ductal adenocarcinoma (PDAC), glioblastoma multiforme (GBM), and triple-negative breast cancer (TNBC) remain largely resistant due to poor immune infiltration, immunosuppressive tumor m...

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Principais autores:	Anshu, Nair Shantikumar V., Roy Sreeja
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-02-01
coleção:	Frontiers in Immunology
Assuntos:	anti-tumor immunity and immunotherapy lymphotoxin beta receptor lymphotoxin beta receptor pleiotropy myeloid reprogramming non-T cell-based immunotherapy novel immunotherapeutic approaches
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1693507/full
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