Role of BMPR2 Mutation in Lung Organoid Differentiation

<b>Background</b>: The bone morphogenetic protein (BMP) signaling pathway is essential for lung development. BMP4, a key regulator, binds to type I (BMPR1) and type II (BMPR2) receptors to initiate downstream signaling. While the inactivation of <i>Bmpr1a</i> and <i>Bmpr1b</i> leads to tracheoesopha...

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Principais autores:	Simin Jiang, Dian Chen, Liangliang Tian, Zihang Pan, Huanyu Long, Lanhe Chu, Weijing Kong, Qiyang Yao, Xiaojing Ma, Yun Zhao, Kai Wang, Yahong Chen
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2025-07-01
叢編:	Biomedicines
主題:	induced pluripotent stem cell airway organoid alveolar organoid pulmonary hypertension BMPR2
在線閱讀:	https://www.mdpi.com/2227-9059/13/7/1623
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