Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers

The majority of human breast cancer is estrogen receptor alpha (ER) positive. While anti-estrogens/aromatase inhibitors are initially effective, resistance to these drugs commonly develops. Therapy-resistant tumors often retain ER signaling, via interaction with critical oncogenic coregulator protei...

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Үндсэн зохиолчид:	Ganesh V Raj, Gangadhara Reddy Sareddy, Shihong Ma, Tae-Kyung Lee, Suryavathi Viswanadhapalli, Rui Li, Xihui Liu, Shino Murakami, Chien-Cheng Chen, Wan-Ru Lee, Monica Mann, Samaya Rajeshwari Krishnan, Bikash Manandhar, Vijay K Gonugunta, Douglas Strand, Rajeshwar Rao Tekmal, Jung-Mo Ahn, Ratna K Vadlamudi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	eLife Sciences Publications Ltd 2017-08-01
Цуврал:	eLife
Нөхцлүүд:	estrogen receptor coregulators coagulator binding modulator endocrine therapy breast cancer
Онлайн хандалт:	https://elifesciences.org/articles/26857
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