Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop

The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics, contributes to cancer drug resistance and the development of gout. In this work, we have analyzed the effects of selected variants, residing in a structurally unresolved cytoplasmic r...

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Principais autores:	Orsolya Mózner, Boglárka Zámbó, Zsuzsa Bartos, Anna Gergely, Kata Sára Szabó, Bálint Jezsó, Ágnes Telbisz, György Várady, László Homolya, Tamás Hegedűs, Balázs Sarkadi
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2023-10-01
叢編:	Membranes
主題:	ABCG2 BCRP MXR multidrug transporter unstructured loop variants
在線閱讀:	https://www.mdpi.com/2077-0375/13/10/822
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!