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Analysis of genetic variation in human papillomavirus type 16 E1 and E2 in women with cervical infection in Xinjiang, China

Abstract Background Xinjiang is one of the regions with a high incidence of cervical cancer, and the genetic variation of human papillomavirus may increase its ability to infect the human body and enhance virus-mediated immune escape ability. Methods Sanger sequencing of the HPV16 genome from 165 sa...

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Main Authors: Luyue Wang, Fang Wang, Shaowei Fu, Chunhe Zhang, Xiangyi Zhe, Hongtao Li, Dongmei Li, Renfu Shao, Zemin Pan
Format: Artigo
Language:Inglês
Published: BMC 2021-11-01
Series:BMC Medical Genomics
Subjects:
Cervical exfoliated cells
Human papillomavirus
E1 and E2 genes
Genetic polymorphism
Sanger sequencing
Online Access:https://doi.org/10.1186/s12920-021-01120-9
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